Description :

Controlled pulmonary drug delivery begins by examination of the foundations for pulmonary drug delivery the macro and microstructure of the airways lung clearance airway absorption and transport aerosol physics and a historical overview of the field unlike other texts these chapters are written specifically with drug delivery in mind. The spatial and temporal control of drug delivery to the airways as a general theme runs through the entire volume from discussions of micro and macro struc ture of the lung particle engineering and polymer science device design to regula tory perspectives and science. In addition to the multiple emulsion method other techniques are also developed to prepare large porous particles for controlled pulmonary drug delivery including precision particle fabrication technology high voltage electrostatic antisolvent method supercritical fluid technology 40 41 42 43 and single emulsion technique 44 45 and their properties for sustained drug release are summarized in table 1. Controlled pulmonary drug delivery is the first book in the crs advances in delivery science and technology series this book is published in partnership with springer and was released in july 2011